It Isn’t All About Plaque
Amyloid beta plaque on the brain has long been associated with Alzheimer’s disease, and often considered the cause of mental decline.
Apparently, this is not true.
A British study used an immune response to almost completely remove the plaque from subjects’ brains, but this did not have any affect on the progression of their dementia.
This stymies the idea of an anti-amyloid approach to fighting Alzheimer’s disease. Even if amyloid beta plaque has something to do with the onset of the disease, it clearly doesn’t have an ongoing affect. Researchers must look for another mechanism triggered concurrently that could be affecting cognition.